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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TWF1
All Species:
35.45
Human Site:
Y53
Identified Species:
70.91
UniProt:
Q12792
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12792
NP_002813.2
350
40283
Y53
S
D
S
W
D
K
D
Y
D
S
F
V
L
P
L
Chimpanzee
Pan troglodytes
XP_001165727
384
43939
Y87
S
D
S
W
D
K
D
Y
D
S
F
V
L
P
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543726
350
40067
Y53
S
D
S
W
D
K
D
Y
D
S
F
V
L
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91YR1
350
40061
Y53
S
D
S
W
E
Q
D
Y
D
S
F
V
L
P
L
Rat
Rattus norvegicus
Q5RJR2
350
40072
Y53
S
D
S
W
E
Q
D
Y
D
P
F
V
L
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508452
357
40765
Y60
A
E
S
W
E
K
D
Y
D
A
F
V
L
P
L
Chicken
Gallus gallus
Q5ZM35
349
39817
Y53
A
R
R
W
D
V
D
Y
D
A
F
V
L
P
L
Frog
Xenopus laevis
Q68F50
350
40436
Y53
T
R
S
W
E
Q
E
Y
D
N
F
I
L
P
L
Zebra Danio
Brachydanio rerio
Q6GMH3
347
39840
P53
S
W
D
K
D
Y
D
P
V
L
L
P
L
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFM9
343
39052
Y53
K
K
D
W
E
R
D
Y
D
K
L
I
G
P
L
Honey Bee
Apis mellifera
XP_393653
350
39782
Y53
V
N
K
W
Q
D
D
Y
D
K
M
I
K
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53250
332
37052
V53
A
R
S
F
E
E
L
V
Q
L
A
S
Q
E
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.6
N.A.
97.7
N.A.
94.8
94.5
N.A.
89.9
66.8
79.7
63.1
N.A.
48.2
53.1
N.A.
N.A.
Protein Similarity:
100
90.6
N.A.
99.1
N.A.
97.7
97.4
N.A.
96.3
86.8
91.1
82.5
N.A.
72.2
74
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
80
N.A.
73.3
66.6
53.3
26.6
N.A.
40
40
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
100
80
93.3
26.6
N.A.
60
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
0
0
0
0
0
17
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
42
17
0
42
9
84
0
84
0
0
0
0
0
9
% D
% Glu:
0
9
0
0
50
9
9
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
67
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% I
% Lys:
9
9
9
9
0
34
0
0
0
17
0
0
9
0
0
% K
% Leu:
0
0
0
0
0
0
9
0
0
17
17
0
75
9
84
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
9
0
9
0
84
0
% P
% Gln:
0
0
0
0
9
25
0
0
9
0
0
0
9
0
0
% Q
% Arg:
0
25
9
0
0
9
0
0
0
0
0
0
0
0
9
% R
% Ser:
50
0
67
0
0
0
0
0
0
34
0
9
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
9
0
9
9
0
0
59
0
0
0
% V
% Trp:
0
9
0
84
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _